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Angle-closure glaucoma as initial presentation of myelodysplastic syndrome
Summary
This study reports a rare case of myelodysplastic syndrome presenting with ciliochoroidal effusion and secondary angle closure glaucoma. These ocular findings were associated with orbital pseudotumor and scleritis.
Area of Science:
- Ophthalmology
- Hematology
- Oncology
Background:
- Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic stem cell disorders.
- Ocular manifestations in MDS are uncommon, with limited reports of orbital inflammation.
Observation:
- A 57-year-old male presented with proptosis and angle-closure glaucoma.
- Further examination revealed bilateral uveal effusions and nonrhegmatogenous retinal detachments.
- Hematologic evaluation confirmed myelodysplastic syndrome.
Findings:
- The patient's ocular findings were attributed to orbital pseudotumor and scleritis.
- This case represents the first reported instance of ciliochoroidal effusion and secondary angle closure in the context of myelodysplastic syndrome.
Implications:
- Highlights a novel association between myelodysplastic syndrome and specific ocular conditions.
- Suggests the need for comprehensive ophthalmologic evaluation in MDS patients with suggestive symptoms.
- Expands the spectrum of known extraskeletal manifestations of myelodysplastic syndromes.