Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
Hypothyroidism II: Pathophysiology01:23

Hypothyroidism II: Pathophysiology

Hypothyroidism is a disorder characterized by insufficient production of thyroid hormones, which regulate metabolism, energy balance, and multiple organ systems.TypesHypothyroidism is classified based on the level of dysfunction. Primary hypothyroidism results from intrinsic thyroid gland dysfunction, causing reduced hormone production despite normal or increased stimulation. Secondary hypothyroidism arises from inadequate thyroid-stimulating hormone (TSH) secretion by the pituitary. Tertiary...
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Graves Disease II: Pathophysiology01:24

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Effect of Intravascular Laser Irradiation of Blood in Functional Outcomes of Ischemic Stroke Patients: A Double-Blind Randomized Control Pilot Study.

Photobiomodulation, photomedicine, and laser surgery·2026
Same author

Reconstruction of advanced oral cancer defects with two or more free flaps: Long-term clinical outcomes.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2026
Same author

Molecular-level insights into the therapeutic potential of lidocaine: effects on proliferation, autophagy, and cellular impedance in human oral cells.

BMC oral health·2026
Same author

Lidocaine enhances antitumor effects of sorafenib and GW5074 in colorectal cancer cells.

Journal of enzyme inhibition and medicinal chemistry·2026
Same author

Case Report: Cervical approach for dual mediastinal ectopic thyroid: clinical utility of 3D imaging in surgical planning.

Frontiers in surgery·2026
Same author

Immune Microenvironment and Genetic Signatures of End-Stage Renal Disease and Their Association with Sepsis: Insights from Public Transcriptomic Data and a Multicenter Clinical Cohort.

Biomedicines·2026
Same journal

The Safety of In-Hospital Delay and the Utility of dNLR in Elderly Patients With Acute Appendicitis.

World journal of surgery·2026
Same journal

Feasibility of Post-Operative Telehealth for Pediatric Surgical Patients in Malawi-A Mixed Methods Analysis.

World journal of surgery·2026
Same journal

Surgical Infrastructure and Workforce Readiness in Rwanda's District and Level 2 Teaching Hospitals: A Nationwide Facility-Based Survey.

World journal of surgery·2026
Same journal

From General Preparedness to Injury-Pattern-Specific Trauma Resource Planning.

World journal of surgery·2026
Same journal

Prevalence and Outcomes of Thrombocytopenia at ICU Admission Among Critically Ill Patients in a Resource-Limited Setting.

World journal of surgery·2026
Same journal

Transition of Care From Pediatric to Adult Services for Patients With Anorectal Malformations: A Qualitative Study.

World journal of surgery·2026
See all related articles

Related Experiment Video

Updated: May 23, 2026

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

Do we overtreat post-thyroidectomy hypocalcemia?

Shih-Ming Huang1

  • 1Department of General Surgery, College of Medicine and Hospital, National Cheng-Kung University, No. 138, Sheng Li Road, 704, Tainan, Taiwan, R.O.C. smhuang@mail.ncku.edu.tw

World Journal of Surgery
|April 12, 2012
PubMed
Summary
This summary is machine-generated.

A quick intraoperative intact parathyroid hormone (QiPTH) assay can guide post-thyroidectomy hypocalcemia treatment. A QiPTH level of 15 ng/L or higher indicates no hypoparathyroidism, preventing overtreatment.

More Related Videos

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

Related Experiment Videos

Last Updated: May 23, 2026

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Neurosurgery

Background:

  • Standard treatment for post-thyroidectomy hypocalcemia involves calcium and calcitriol supplements for serum calcium <2.0 mmol/L.
  • The study questions whether current treatment protocols for post-thyroidectomy hypocalcemia may lead to overtreatment, particularly concerning intraoperative parathyroid hormone (PTH) levels.

Purpose of the Study:

  • To evaluate the utility of the quick-intraoperative intact PTH (QiPTH) assay in managing post-thyroidectomy hypocalcemia.
  • To determine a reliable threshold for the QiPTH assay to predict postoperative parathyroid function and guide treatment decisions.

Main Methods:

  • A cohort of 197 patients undergoing bilateral thyroidectomy was studied.
  • Post-thyroidectomy hypocalcemia was defined as serum calcium <2.0 mmol/L.
  • A QiPTH assay was performed 15 minutes after surgery (QiPTH(15)); hypoparathyroidism was defined as PTH <15 ng/L.

Main Results:

  • No patients with a QiPTH(15) ≥ 15 ng/L developed postoperative hypoparathyroidism.
  • 79 patients experienced transient hypocalcemia, with a higher incidence in those with Graves' disease.
  • Most patients with transient hypocalcemia recovered spontaneously or with calcium supplementation alone, without the need for calcitriol.

Conclusions:

  • A post-thyroidectomy QiPTH(15) level of ≥ 15 ng/L effectively excludes postoperative hypoparathyroidism.
  • While over one-third of patients developed transient hypocalcemia, most resolved without intervention or with minimal calcium supplementation.
  • Utilizing the QiPTH(15) assay can help prevent overtreatment of post-thyroidectomy hypocalcemia, optimizing patient management.