Related Experiment Video

Updated: May 23, 2026

Preparation of Cell-lines for Conditional Knockdown of Gene Expression and Measurement of the Knockdown Effects on E4orf4-Induced Cell Death
13:54

Preparation of Cell-lines for Conditional Knockdown of Gene Expression and Measurement of the Knockdown Effects on E4orf4-Induced Cell Death

Published on: October 21, 2012

High-content analysis of proapoptotic EphA4 dependence receptor functions using small-molecule libraries

Claudiu M Nelersa1, Henry Barreras, Erik Runko

  • 1The Miami Project to Cure Paralysis and Department of Neurosurgery, University of Miami School of Medicine, Miami, FL 33136, USA.

Journal of Biomolecular Screening
|April 12, 2012
PubMed
Summary

Researchers screened small-molecule compounds (SMCs) to find inhibitors of EphA4-mediated cell death. This study developed a high-content analysis (HCA) method to identify compounds that regulate dependence receptor signaling pathways.

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