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The Attentional Set Shifting Task: A Measure of Cognitive Flexibility in Mice
09:15

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Published on: February 4, 2015

Cognitive set-shifting in anorexia nervosa.

Megan E Shott1, J Vincent Filoteo, Kelly A C Bhatnagar

  • 1Department of Psychiatry, University of Colorado Denver, CO, USA.

European Eating Disorders Review : the Journal of the Eating Disorders Association
|April 12, 2012
PubMed
Summary
This summary is machine-generated.

Cognitive flexibility and set-shifting are not impaired in adolescents with anorexia nervosa (AN). However, adults with AN show significant set-shifting deficits, suggesting developmental changes in the disorder.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Adult anorexia nervosa (AN) is linked to cognitive inflexibility, specifically in set-shifting.
  • It remains unclear if similar cognitive deficits are present in adolescent AN.

Purpose of the Study:

  • To investigate cognitive flexibility and set-shifting abilities in adolescents with AN.
  • To compare these abilities with those of adult AN patients and healthy controls.

Main Methods:

  • Adolescents and adults with AN, along with matched controls, completed a computerized rule-learning and set-shifting task.
  • Performance was assessed based on set-shifting cost, a measure of cognitive flexibility.

Main Results:

  • Adolescent AN patients showed no significant difference in set-shifting cost compared to controls.
  • Adult AN patients exhibited significantly higher set-shifting costs than adult controls.

Conclusions:

  • Set-shifting inefficiency may not be an early vulnerability factor for AN development in adolescents.
  • These deficits may emerge later in the disorder, potentially reflecting neurobiological changes across different age groups.