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[Significance of the circulating antibodies in patients with interstitial lung disease]

X F Jiang1

  • 1Peking Union Medical College Hospital, Beijing.

Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases
|June 1, 1990
PubMed

Indirect immunofluorescent study was proceeded in 86 cases of interstitial lung disease by using human fetal lung as the target organ. 2 kinds of antibodies were found. One was type I or III anticollagen antibody, the positive rate in IPF was the highest, 63%. The other was antinuclear antibody (ANA). 8 cases were positive. Both of the antibodies may play active role in the pathogenesis of IPF. The authors suggest that assessment of the antibodies to college type L & III by immunofluorescent method might be helpful in the diagnosis of IPF.

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