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Lip cancer: a 10-year retrospective epidemiological study
M Maruccia1, M G Onesti, P Parisi
1Department of Plastic and Reconstructive Surgery, Sapienza University, Rome, Italy. marucciam@gmail.com
Anticancer Research
|April 12, 2012
Summary
Lip cancer, a common oral-maxillary tumor, disproportionately affects men over 45. Key risk factors include sun exposure, tobacco, and alcohol, particularly for squamous cell carcinoma.
Area of Science:
- Oncology
- Dermatology
- Epidemiology
Background:
- Lip cancer is the most common tumor in the oral-maxillary region.
- A high incidence of lip cancer has been observed in Italy over the last decade.
Purpose of the Study:
- To analyze epidemiological data and risk factors for lip cancer.
- To investigate the association between risk factors and squamous cell carcinoma of the lip.
Main Methods:
- Retrospective study of 540 lip cancer cases (2000-2010).
- Epidemiological data and risk factor analysis.
- Statistical analysis using Student T and Chi-square tests.
Main Results:
- Most cases (82%) occurred in men, and 84.8% in individuals over 45.
- Squamous cell carcinoma of the external lower lip was the dominant type, predominantly in men.
- High rates of chronic solar exposure, tobacco, and alcohol use were recorded.
Conclusions:
- Individuals over 45 are at increased risk for lip cancer.
- Sun exposure, tobacco, and alcohol are significantly associated with squamous cell carcinoma development.
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