Cell-culture Database: Literature-based reference tool for human and mammalian experimentallybased cell culture...

Area of Science:

• Biotechnology
• Cell Biology
• Molecular Biology

Background:

• Cell and tissue culture advancements are crucial for biotechnology and viral vaccine production.
• Progress in human and mammalian cell transfection and transduction drives fields like cancer research and genetics.
• The growing volume of cell culture literature presents challenges in accessing specific, practical information.

Purpose of the Study:

• To create a user-friendly database consolidating cell line, plasmid, and vector information.
• To address the challenge of information retrieval from extensive cell culture literature.
• To support researchers in biotechnology and molecular biology.

Main Methods:

• Compiled data on over 3,900 human and mammalian cell lines.
• Included information on 1,900 plasmids and vectors.
• Extracted data from 2,700 published scientific literature sources.

Main Results:

• Developed a practical database containing cell lines, plasmids, vectors, selection agents, concentrations, and media.
• The database currently houses extensive data from diverse scientific publications.
• The resource is continuously updated with new information.

Conclusions:

• The database provides a centralized, accessible resource for cell and molecular biologists.
• It aims to enrich the work of life-science professionals by simplifying data access.
• Ongoing expansion of the database will enhance its utility for the global scientific community.