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Published on: February 8, 2019
Steroid-induced sigmoid diverticular perforation in a patient with temporal arteritis: a rare clinical pathology
Bulent Kaya1, Orhan Aras, Orhan Bat
1Fatih Sultan Mehmet Training and Research Hospital, Department of General Surgery, Istanbul, Turkey.
Abstract:
Corticosteroids are used in the treatment of many rheumatological diseases including temporal arteritis. The gastrointestinal perforation during corticosteroid treatment is a serious complication. Colon perforation after steroid use was first reported by Beck et al in 1950.1 Although the pathophysiological mechanism is not understood clearly, it is claimed that steroids probably by disturbing the intestinal mucosal barrier, facilitate the intestinal perforation. The long term treatment with corticosteroids increases the risk of colon perforation. We are presenting a patient who was taking corticosteroid due to temporal arteritis for two years and operated with sigmoid diverticular perforation.
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