Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

FISH - Fluorescent In-situ Hybridization02:07

FISH - Fluorescent In-situ Hybridization

Fluorescence in situ hybridization, or FISH, was developed in the early 1980s and has quickly become one of the most widely used techniques in cytogenetics. Labeled probes are used to bind complementary DNA or RNA sequences on a chromosome or in a region within a cell. Earlier, the probes could only be obtained by cloning or reverse transcription of a DNA template. Currently, the probe oligonucleotides can be synthesized synthetically. Additionally, with the advancement of optical techniques,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spatially resolved EEG reveals theta-band network modulation following iTBS in aging and mild cognitive impairment.

Frontiers in human neuroscience·2026
Same author

Brain Morphology and Quantitative Assessment of Sensory Brain Areas in Southern Bluefin Tuna, Thunnus maccoyii (Scombridae, Teleostei).

The Journal of comparative neurology·2026
Same author

The Role of Temperature in Shaping the Nervous System Phenotype in the Epaulette Shark (<italic>Hemiscyllium ocellatum</italic>).

Brain, behavior and evolution·2026
Same author

The wave nature of the action potential.

Frontiers in cellular neuroscience·2025
Same author

Meningeal Lymphatic and Glymphatic Structures in a Pelagic Delphinid (<i>Delphinus delphis</i>).

Animals : an open access journal from MDPI·2025
Same author

Diffusion tensor subspace imaging of double diffusion-encoded MRI delineates small fibers and gray-matter microstructure not visible with single encoding techniques.

Magnetic resonance in medicine·2025

Related Experiment Video

Updated: May 23, 2026

Morphometric Analyses of Shape: The Analysis Software Toolbox for Craniofacial Shape Quantification in Zebrafish
09:03

Morphometric Analyses of Shape: The Analysis Software Toolbox for Craniofacial Shape Quantification in Zebrafish

Published on: February 27, 2026

The Digital Fish Library: using MRI to digitize, database, and document the morphological diversity of fish.

Rachel M Berquist1, Kristen M Gledhill, Matthew W Peterson

  • 1Center for Scientific Computation in Imaging, University of California San Diego, La Jolla, California, United States of America.

Plos One
|April 12, 2012
PubMed
Summary

The Digital Fish Library (DFL) archives 3D MRI scans of fish anatomy, providing researchers and educators with accessible digital morphology data. This non-invasive imaging method preserves specimens while enabling detailed biodiversity studies.

More Related Videos

Wireless Electrophysiological Recording of Neurons by Movable Tetrodes in Freely Swimming Fish
10:14

Wireless Electrophysiological Recording of Neurons by Movable Tetrodes in Freely Swimming Fish

Published on: November 26, 2019

Behavioral Tracking and Neuromast Imaging of Mexican Cavefish
14:58

Behavioral Tracking and Neuromast Imaging of Mexican Cavefish

Published on: April 6, 2019

Related Experiment Videos

Last Updated: May 23, 2026

Morphometric Analyses of Shape: The Analysis Software Toolbox for Craniofacial Shape Quantification in Zebrafish
09:03

Morphometric Analyses of Shape: The Analysis Software Toolbox for Craniofacial Shape Quantification in Zebrafish

Published on: February 27, 2026

Wireless Electrophysiological Recording of Neurons by Movable Tetrodes in Freely Swimming Fish
10:14

Wireless Electrophysiological Recording of Neurons by Movable Tetrodes in Freely Swimming Fish

Published on: November 26, 2019

Behavioral Tracking and Neuromast Imaging of Mexican Cavefish
14:58

Behavioral Tracking and Neuromast Imaging of Mexican Cavefish

Published on: April 6, 2019

Area of Science:

  • Ichthyology
  • Biodiversity Science
  • Digital Morphology

Background:

  • Museum fish collections hold valuable anatomical and morphological data crucial for biodiversity research.
  • Accessing physical specimens can be impractical and risk specimen integrity.
  • Non-invasive 3D digital imaging offers a solution for specimen digitization and data sharing.

Purpose of the Study:

  • To develop the Digital Fish Library (DFL) as an online archive for 3D magnetic resonance imaging (MRI) scans of fish soft tissue anatomy.
  • To create a system for data archival, retrieval, and web-based analysis and visualization.
  • To make high-resolution digital morphology data freely accessible to researchers and educators.

Main Methods:

  • Utilized magnetic resonance imaging (MRI) to capture high-resolution, high-contrast scans of fish soft tissue anatomy.
  • Developed a data archival and retrieval system with integrated web-based image analysis and visualization tools.
  • Uploaded MRI data for over 300 marine and freshwater fish species to the DFL website.

Main Results:

  • Successfully created an online digital archive (DFL) of 3D MRI scans for over 300 fish species.
  • Demonstrated MRI as a rapid and effective method for detailed in-situ soft tissue anatomy depiction.
  • Established a public website for free dissemination of digital morphology data and metadata.

Conclusions:

  • The Digital Fish Library provides a valuable resource for large-scale comparative digital morphology studies.
  • MRI is a powerful non-invasive technique for preserving and analyzing anatomical data from museum specimens.
  • A robust computational and archival infrastructure is essential for broad accessibility of 3D volumetric data.