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Multifocal osteonecrosis associated with human immunodeficiency virus infection
Andrés González García1, Walter Alberto Sifuentes Giraldo, María Ángeles Blázquez Cañamero
1Servicio de Medicina Interna, Hospital Universitario Ramón y Cajal, Madrid, España. andres_gonzalez_garcia@hotmail.com
Reumatologia Clinica
|April 13, 2012
Summary
HIV patients face a higher risk of osteonecrosis, a disabling bone complication. This case highlights multifocal osteonecrosis affecting hips, knees, heels, and tarsus in an HIV-infected individual on antiretroviral therapy.
Area of Science:
- Orthopedics
- Infectious Diseases
- HIV Medicine
Background:
- Osteonecrosis is an emerging complication in patients with Human Immunodeficiency Virus (HIV) infection.
- HIV-infected individuals often present with traditional osteonecrosis risk factors, alongside factors related to HIV itself and highly active antiretroviral therapy (HAART).
- While hip osteonecrosis, often bilateral, is common, multifocal osteonecrosis affecting three or more sites is infrequently reported.
Observation:
- A 49-year-old male patient with a long history of HIV infection and HAART was observed.
- The patient developed osteonecrosis affecting multiple joints.
Findings:
- The patient presented with concomitant osteonecrosis of the hips, knees, heels, and tarsus.
- This case represents an infrequent occurrence of multifocal osteonecrosis in an HIV-infected patient.
Implications:
- This case underscores the potential for extensive osteonecrosis in HIV-infected patients, even with multiple joint involvement.
- Understanding the interplay of HIV, HAART, and osteonecrosis is crucial for managing this disabling complication.
- Further research into the specific mechanisms and risk factors for multifocal osteonecrosis in HIV is warranted.
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