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Urinary tract infections in children: a review
1Sacro Cuore Catholic University, Rome, Italy. danilobuonsenso@gmail.com
Insights
Febrile urinary tract infections (UTIs) are common in children. Current guidelines for diagnosis, treatment, and imaging after a first UTI lack universal acceptance, necessitating further research for optimal management.
Area of Science:
- Pediatrics
- Infectious Diseases
- Urology
Background:
- Febrile urinary tract infection (UTI) represents a significant bacterial infection in pediatric populations.
- Optimal diagnostic and management strategies following a child's initial UTI remain subjects of ongoing clinical discussion and research.
Purpose of the Study:
- To review current recommendations for the diagnosis, treatment, imaging evaluation, and antibiotic prophylaxis in children experiencing their first febrile UTI.
- To highlight the ongoing lack of a universally accepted diagnostic protocol for pediatric febrile UTIs.
Main Methods:
- Systematic review of current clinical guidelines and recommendations.
- Analysis of diagnostic criteria, therapeutic interventions, and imaging modalities.
- Evaluation of antibiotic prophylaxis strategies in pediatric febrile UTI cases.
Main Results:
- Febrile UTI is the most frequent serious bacterial infection encountered in childhood.
- Significant variability exists in recommended diagnostic and management approaches, including imaging and prophylaxis.
- A consensus on a universal diagnostic protocol for pediatric febrile UTI has not yet been established.
Conclusions:
- The optimal evaluation and long-term management of children following a first febrile UTI require further clarification.
- Standardization of diagnostic protocols is essential for consistent and effective care of pediatric febrile UTIs.
Abstract:
Febrile urinary tract infection is the most common serious bacterial infection in childhood, but the most appropriate evaluation of children with this condition is still unclear, overall regarding the best long-term management of children after a first UTI. Here we review current recommendations for the diagnosis, treatment, imaging evaluation and use of antibiotic prophylaxis in children with the first febrile urinary tract infection. Nevertheless, the development of a universally accepted diagnostic protocol remains elusive.
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