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Updated: May 23, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
Intraoperative use of a chest physiotherapy system during whole lung lavage for pulmonary alveolar proteinosis
Avinash B Kumar1, Hans W Schweiger
1University of Iowa, Department of Anesthesia, 200 Hawkins Drive, 5JCP, Iowa City, IA 52242, USA. avinash-kumar@uiowa.edu
Abstract:
Pulmonary alveolar proteinosis (PAP) is a rare condition caused by the excessive alveolar accumulation of surfactant proteins. The current standard of care for removing these secretions is through therapeutic whole lung lavage (WLL). We describe two successful cases of bilateral WLL involving the novel use of the Vest™ chest physiotherapy system thereby avoiding the need for extensive changes in patient position in the intraoperative period. In brief, it involves the induction of general anesthesia followed by single-lung ventilation while simultaneously performing large volume lavages on the nonventilated lung. The washout was enhanced using the Vest™ system.
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Chest Physiotherapy
Purpose
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Clinical Manifestations:
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Assessment:
1. Clinical Evaluation:
History: