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Related Concept Videos

Motor Unit Stimulation01:20

Motor Unit Stimulation

When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...

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Construction of Local Field Potential Microelectrodes for in vivo Recordings from Multiple Brain Structures Simultaneously
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Local field potentials allow accurate decoding of muscle activity.

Robert D Flint1, Christian Ethier, Emily R Oby

  • 1Department of Neurology, Northwestern University, Chicago, IL 60611, USA.

Journal of Neurophysiology
|April 13, 2012
PubMed
Summary

Local field potentials (LFPs) provide robust signals for decoding upper limb muscle activity. This finding suggests LFPs are a valuable, long-lasting signal source for advanced neural prostheses.

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Area of Science:

  • Neuroscience
  • Motor Control
  • Biomedical Engineering

Background:

  • Local field potentials (LFPs) in the primary motor cortex contain information about reach targets and movement kinematics.
  • LFPs may offer more robust and longer-lasting neural signals compared to action potentials (spikes).

Purpose of the Study:

  • To investigate if LFPs can decode upper limb muscle activity, a complex motor signal.
  • To compare the decoding performance of LFPs against spikes for muscle activity.

Main Methods:

  • Electromyograms (EMGs) were recorded from proximal and distal upper limb muscles in monkeys.
  • Monkeys performed reach-to-grasp and isometric wrist force tasks during neural recordings.

Main Results:

  • LFPs successfully decoded activity from both proximal and distal upper limb muscles.
  • Decoding performance using LFPs rivaled that achieved using spikes.

Conclusions:

  • Motor cortical LFPs encode a wider range of movement aspects than previously recognized.
  • LFPs represent a promising, durable signal for neural prosthetics development.