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Updated: May 23, 2026
05:42
Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation
Published on: October 25, 2024
Fertility preservation in girls
Jennia Michaeli1, Michael Weintraub, Eitan Gross
1Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, 91120 Jerusalem, Israel.
Obstetrics and Gynecology International
|April 13, 2012
Summary
Ovarian cryopreservation before cancer treatment helps preserve fertility in young girls. This review revises guidelines for offering this option to premenarcheal patients.
Area of Science:
- Pediatric Oncology
- Reproductive Endocrinology
- Bioethics
Background:
- Cancer treatments like chemotherapy and radiotherapy can cause infertility in children.
- Preserving reproductive potential is crucial for pediatric cancer survivors.
- Ovarian tissue cryopreservation offers a method to restore gonadal function post-treatment.
Purpose of the Study:
- To review recent literature on ovarian cryopreservation for pediatric cancer patients.
- To update recommendations from a 2007 article.
- To propose guidelines for offering ovarian cryopreservation to premenarcheal girls.
Main Methods:
- Literature review of recent studies.
- Integration of perspectives from pediatric hemato-oncology, reproductive endocrinology, surgery, anesthesia, and bioethics.
- Development of revised guidelines.
Main Results:
- The review synthesizes current knowledge on the risks and benefits of ovarian cryopreservation.
- Multidisciplinary input is essential for effective patient counseling and management.
- Updated guidelines are proposed for offering the procedure.
Conclusions:
- Ovarian cryopreservation is a viable option for preserving fertility in premenarcheal girls undergoing cancer treatment.
- Comprehensive counseling and a multidisciplinary approach are vital.
- Revised guidelines aim to optimize the offering of this fertility preservation method.
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