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Meconium pseudocyst with particular pathologic findings: a case report and review of the literature
Masashi Minato1, Tadao Okada, Hisayuki Miyagi
1Department of Pediatric Surgery, Hokkaido University Hospital, Sapporo, Japan. greatmarkn@yahoo.co.jp
Abstract:
Meconium peritonitis is a sterile chemical peritonitis caused by bowel perforation with intraperitoneal extravasation of the meconium in utero. When the inflamed intestinal loops become fixed, meconium peritonitis leads to a cystic cavity with a fibrous wall, and the result is termed cystic-type meconium peritonitis. On the contrary, a meconium pseudocyst has a muscle layer continuous with the normal intestine and is distinguished from cystic-type meconium peritonitis based on the histopathologic findings. This report describes the rare case of a neonate complicated by a meconium pseudocyst, which was successfully treated with 1-stage resection and primary anastomosis. There have been few cases of meconium pseudocysts reported in the literature. Meconium peritonitis should be considered in the differential diagnosis in patients who develop large abdominal cysts with air and fluid content. Cystic-type meconium peritonitis is usually treated using drainage with subsequent elective surgery. However, for a meconium pseudocyst, 1-stage intestinal resection with primary anastomosis may be recommended. A meconium pseudocyst may be treatable using 1-stage resection based on histopathologic features.
Insights
Meconium pseudocyst, a rare condition causing abdominal cysts in neonates, can be successfully treated with single-stage intestinal resection and primary anastomosis. This approach differs from typical meconium peritonitis management.
Area of Science:
- Neonatal surgery
- Pediatric gastroenterology
- Surgical pathology
Background:
- Meconium peritonitis arises from in utero bowel perforation and meconium extravasation.
- Cystic-type meconium peritonitis forms a fibrous-walled cavity, distinct from meconium pseudocysts.
- Meconium pseudocysts possess a muscle layer continuous with normal intestine, identified via histopathology.
Observation:
- This report details a rare case of a neonate with a meconium pseudocyst.
- The neonate presented with a large abdominal cyst containing air and fluid.
- Meconium peritonitis is a key differential diagnosis for such presentations.
Findings:
- The neonate's meconium pseudocyst was successfully treated with a one-stage resection and primary anastomosis.
- Histopathologic features are crucial for distinguishing meconium pseudocysts from cystic-type meconium peritonitis.
- Few cases of meconium pseudocysts have been documented in medical literature.
Implications:
- One-stage intestinal resection with primary anastomosis may be the recommended treatment for meconium pseudocysts.
- Accurate histopathologic diagnosis is vital for guiding surgical strategy.
- This case highlights a potentially effective treatment for a rare neonatal surgical condition.
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