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Pseudoaneurysm of the mitral-aortic intervalvular fibrosa
Mingxing Xie1, Yuman Li, Tsung O Cheng
1Department of Ultrasonography, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Hubei Provincial Key Laboratory of Molecular Imaging, Wuhan 430022, People's Republic of China.
Abstract:
Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) is a rare but potentially fatal complication of infective endocarditis and aortic valve surgery. 149 patients with P-MAIVF, including 7 cases in our hospital and 142 cases from the literatures, were comprehensively analyzed. P-MAIVF is located in the mitral-aortic intervalvular fibrosa area, which communicates with the left ventricular outflow tract. The cavity of P-MAIVF expands during systole and collapses during diastole. Endocarditis and aortic valve surgery are the most frequent causes. Symptoms of endocarditis, chest pain, heart failure, dyspnea, cerebrovascular accidents and systemic embolism are important clinical presentations. The formation of a fistulous tract, coronary artery compression, and rupture into pericardium are important complications. Transesophageal echocardiography is superior to transthoracic echocardiography in identifying P-MAIVF. Surgery is the treatment of choice with P-MAIVF repair and aortic valve replacement.
Insights
Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) is a rare complication of endocarditis and aortic valve surgery. Surgical repair and aortic valve replacement are the primary treatments for this condition.
Area of Science:
- Cardiovascular Surgery
- Cardiology
- Medical Imaging
Background:
- Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (P-MAIVF) is a rare but life-threatening condition.
- It often arises as a complication of infective endocarditis or aortic valve surgery.
Purpose of the Study:
- To comprehensively analyze the characteristics, clinical presentations, complications, and management of P-MAIVF.
- To evaluate diagnostic modalities and surgical outcomes for P-MAIVF.
Main Methods:
- Retrospective analysis of 149 patients with P-MAIVF (7 from the authors' institution, 142 from literature).
- Review of clinical data, imaging findings, and treatment outcomes.
- Comparison of diagnostic accuracy between transesophageal echocardiography (TEE) and transthoracic echocardiography (TTE).
Main Results:
- P-MAIVF is located in the mitral-aortic intervalvular fibrosa, communicating with the left ventricular outflow tract.
- Common causes include endocarditis and aortic valve surgery; common presentations include chest pain, heart failure, and embolism.
- TEE demonstrated superior diagnostic capability compared to TTE for P-MAIVF detection.
Conclusions:
- P-MAIVF requires prompt diagnosis and surgical intervention.
- Surgical repair combined with aortic valve replacement is the preferred treatment strategy.
- Understanding P-MAIVF's pathophysiology and complications is crucial for effective management.
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