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Role of Skin in Vitamin D Synthesis

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).

Vitamins

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...

Role of Vitamins in Maintaining Bone Health

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Dosage Regimen: Fixed Dose

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Related Experiment Video

Updated: May 23, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

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Correcting vitamin D deficiency using over-the-counter supplements.

Anna Dunlap¹, Amy Rudenko

¹Walgreen's, Richmond, Virginia 23298, USA.

The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists

|April 14, 2012

Summary

This case study shows how a community pharmacy enhanced patient care by adjusting vitamin D3 supplementation. The patient

Area of Science:

Endocrinology
Pharmacology
Public Health

Background:

Vitamin D deficiency is a prevalent health concern, particularly in individuals with specific risk factors such as race, weight, and age.
Community pharmacies play a vital role in medication therapy management, offering services to address common health issues like vitamin D deficiency.

Observation:

A patient presented with insufficient response to over-the-counter vitamin D3 supplementation for deficiency.
The patient exhibited risk factors including race, weight, and age, contributing to her low vitamin D levels.

Findings:

Literature review established the patient's indication for supplementation and determined a target serum level of 30-40 ng/dL.
Initial supplementation with 1,000 IU daily increased serum levels from 10.2 ng/dL to 22.1 ng/dL over four months.

Related Experiment Videos

Last Updated: May 23, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Increasing the dosage to 2,000 IU daily successfully raised the patient's vitamin D level to 35.4 ng/dL within three months, achieving the therapeutic goal.

Implications:

Personalized medication therapy management in community pharmacies can effectively optimize vitamin D supplementation regimens.
Achieving and maintaining adequate vitamin D levels is crucial for patient health, especially for those with deficiency risk factors.
Pharmacist intervention, in collaboration with physicians, can lead to improved patient outcomes in managing vitamin D deficiency.