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Plasmodesmata

Plasmodesmata

The organs in a multicellular organism’s body are made up of tissues formed by cells. To work together cohesively, cells must communicate. One way that cells communicate is through direct contact with other cells. The points of contact that connect adjacent cells are called intercellular junctions.

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Updated: May 23, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

Plasmablastic extramedullary plasmacytoma.

Irulandy Ponniah¹, Suhasini Rajan

¹Department of Oral and Maxillofacial Pathology, Tamil Nadu Government Dental College and Hospital, Chennai, Tamil Nadu, India. salivaryduct@yahoo.co.uk

Indian Journal of Pathology & Microbiology

|April 14, 2012

Summary

Extramedullary plasmacytoma is a rare soft tissue tumor. This case highlights the diagnostic challenges and successful radiotherapy treatment of a plasmablastic variant in the gingiva.

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Intracranial Orthotopic Allografting of Medulloblastoma Cells in Immunocompromised Mice

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Published on: October 3, 2010

Area of Science:

Oncology
Pathology

Background:

Extramedullary plasmacytoma (EMP) is a plasma cell neoplasm occurring outside bone marrow.
Distinguishing EMP from other plasma cell disorders and lymphomas can be challenging due to overlapping features.

Observation:

A case of plasmablastic extramedullary plasmacytoma in a 52-year-old patient's mandibular lingual gingiva is presented.
The lesion exhibited morphological and immunohistochemical similarities to plasmablastic lymphoma, complicating diagnosis.

Findings:

The diagnosis of plasmablastic extramedullary plasmacytoma was established.
The gingival mass showed significant regression following primary radiotherapy.

Implications:

This case underscores the importance of considering plasmablastic extramedullary plasmacytoma in the differential diagnosis of gingival masses.
Radiotherapy can be an effective treatment modality for localized plasmablastic extramedullary plasmacytoma.