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Related Concept Videos

Human Virome01:26

Human Virome

The human body harbors a vast and diverse viral community known as the human virome. The virome includes bacteriophages that infect bacteria, and eukaryotic viruses that infect human cells. Transient dietary and environmental viruses also contribute to this dynamic ecosystem. Estimates suggest the human body may contain on the order of 10¹³ viral particles, though abundance varies widely by body site and detection method.Comprehensive characterization of the virome has become possible only with...
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Genetic Variation01:25

Genetic Variation

Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles, which...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.

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Updated: May 23, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
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Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Published on: December 27, 2010

The Human Variome Project Beijing meeting.

Timothy D Smith1, Helen M Robinson, Richard G H Cotton

  • 1Human Variome Project International Ltd, Melbourne,Victoria, Australia. tim@variome.org

Journal of Medical Genetics
|April 14, 2012
PubMed
Summary

The Human Variome Project aims to openly share genetic variation data. This Beijing meeting formalized the Chinese Node

Area of Science:

  • Genomics and Bioinformatics
  • Human Genetics and Disease Databases

Background:

  • The Human Variome Project (HVP) is an international initiative dedicated to collecting, curating, interpreting, and openly sharing all genetic variation data.
  • Genetic variation is crucial for understanding human health, disease, and evolution.

Framework:

  • The HVP operates on principles of free and open data sharing to facilitate global research.
  • It aims to establish comprehensive gene/disease-specific databases.

Implementation:

  • The Beijing Meeting (December 8th-12th, 2011) was a joint event of the HVP Consortium and the HVP Chinese Node.
  • This meeting officially integrated the HVP Chinese Node as a key partner.
  • Focus was placed on collaborative efforts between China and the global HVP Consortium to expand international gene/disease databases.

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Last Updated: May 23, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
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Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Published on: December 27, 2010

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

Implications:

  • Enhanced collaboration with the HVP Chinese Node will accelerate the development and coverage of international genetic variation databases.
  • Openly shared genetic variation data will advance genomic medicine and our understanding of human diseases.
  • This partnership strengthens the global infrastructure for managing and utilizing human genetic information.