Related Experiment Video
Updated: May 23, 2026
06:45
A Modified Cuff Technique for Mouse Cervical Heterotopic Heart Transplantation Model
Published on: February 7, 2022
Short crossclamp heart transplantation: a modified technique
Ali Reza Bakhshandeh1, Mehrdad Salehi, Hasan Radmehr
1Department of Cardiovascular Surgery, Imam Medical Complex, Tehran University of Medical Sciences, Tehran, Iran. abakhshandeh@ymail.com
Asian Cardiovascular & Thoracic Annals
|April 14, 2012
Summary
A modified short crossclamp technique in heart transplantation significantly reduces crossclamp time and improves donor heart performance. This method facilitates easier separation from bypass and better postoperative echocardiographic systolic parameters.
Area of Science:
- Cardiovascular Surgery
- Transplantation Medicine
- Surgical Techniques
Background:
- Prolonged ischemic time negatively impacts donor heart function after heart transplantation.
- The conventional bicaval method involves a longer crossclamp period.
Purpose of the Study:
- To compare the impact of ischemic time using the conventional bicaval method versus a modified short crossclamp technique in heart transplantation.
- To evaluate the effects of a modified technique on donor heart performance and postoperative outcomes.
Main Methods:
- A comparative study involving 58 heart transplant patients.
- Group A (n=30) underwent the conventional bicaval method.
- Group B (n=28) utilized a modified short crossclamp technique with earlier declamping.
Main Results:
- Mean crossclamp time was significantly shorter in the modified technique group (62.4 min) compared to the conventional group (80.5 min).
- Fewer patients in the modified group required inotropic support or intraaortic balloon pumping postoperatively.
- Faster weaning from cardiopulmonary bypass and more complete de-airing were observed in the modified technique group.
- Postoperative transesophageal echocardiography showed improved systolic parameters in the modified group.
Conclusions:
- The modified short crossclamp technique offers advantages including reduced ischemic time and improved early graft function.
- This technique facilitates easier separation from cardiopulmonary bypass and better postoperative hemodynamic stability.
- No significant differences were noted in ICU stay or postoperative neurologic complications between the groups.
