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Published on: June 23, 2022
Percutaneous iatrogenic coronary fistula closure in heart transplant recipient
Giuseppe Bruschi1, Jacopo Oreglia, Paola Colombo
1A De Gasperis Cardiology and Cardiac Surgery Department, Niguarda Ca' Granda Hospital, Milan, Italy. giuseppe.bruschi@fastwebnet.it
Insights
A large coronary artery fistula between the left anterior descending artery and the right ventricle was identified post-heart transplant. This fistula was successfully treated with a covered stent when ischemic symptoms developed 8 years later.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Transplantation Medicine
Background:
- Ischemic cardiomyopathy necessitates orthotopic heart transplantation for end-stage heart failure.
- Post-transplant monitoring includes routine coronary angiography to assess graft health and detect complications.
Observation:
- A significant coronary artery fistula, originating from the left anterior descending artery and draining into the right ventricle, was incidentally discovered one year after heart transplantation.
- The patient remained asymptomatic for eight years following the initial diagnosis of the fistula.
Findings:
- The coronary artery fistula was successfully occluded percutaneously using a covered stent.
- Percutaneous closure effectively resolved the patient's subsequent ischemic symptoms.
Implications:
- Coronary artery fistulas are rare but significant complications following orthotopic heart transplantation.
- Percutaneous closure with covered stents offers a viable and effective treatment option for symptomatic coronary artery fistulas in heart transplant recipients.
Abstract:
A 61-year-old man with ischemic cardiomyopathy underwent orthotopic heart transplantation. On routine coronary angiography 1 year later, a huge fistula was seen between the left anterior descending coronary artery and the right ventricle. When the patient developed symptoms of ischemia 8 years later, the fistula was successfully closed percutaneously, using a covered stent.

