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Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
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Advancing the STATus of MPN pathogenesis

Neil P Shah1, Kevin Shannon

  • 1University of California, San Francisco, CA, USA.

Blood
|April 14, 2012
PubMed
Summary

Signal transducer and activator of transcription 5 (STAT5) is crucial for abnormal hematopoietic cell growth in myeloproliferative neoplasms (MPNs). Targeting STAT5 pathways offers therapeutic potential for MPN patients.

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