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Intrasellar chondroid chordoma: a case report.
Renata M Hirosawa1, Antonio B A Santos, Mariana M França
1Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine of Botucatu, UNESP, 18618-970 Botucatu, SP, Brazil.
ISRN Endocrinology
|April 14, 2012
Summary
Chordomas are rare tumors originating from notochord remnants. This case highlights a chondroid chordoma in the sellar region, presenting symptoms like vision loss and hypopituitarism.
Area of Science:
- Neuro-oncology
- Endocrinology
- Surgical Pathology
Background:
- Chordomas are uncommon malignant bone tumors arising from notochordal remnants, predominantly in the midline.
- Intrasellar chordomas are exceptionally rare, posing diagnostic challenges due to their location and presentation.
- Pituitary adenomas are common sellar tumors, often sharing similar clinical symptoms with other sellar masses.
Observation:
- A 57-year-old male presented with retro-orbital headache, vision loss, and hypopituitarism over two months.
- CT imaging revealed a large, contrast-enhancing intrasellar tumor measuring 3.6 cm.
- The patient underwent transsphenoidal partial tumor resection.
Findings:
- Histological examination confirmed the diagnosis of chondroid chordoma.
- The tumor exhibited characteristics consistent with a rare intrasellar chordoma.
- The clinical presentation mimicked that of a pituitary adenoma.
Implications:
- Chordomas should be considered in the differential diagnosis of intrasellar tumors, particularly pituitary adenomas.
- Radiological findings such as calcification and bone erosion may suggest chordoma over pituitary adenoma.
- Early and accurate diagnosis is crucial for appropriate management of rare sellar chordomas.