Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
Self-Schemas02:16

Self-Schemas

In general, a schema is a mental construct consisting of a cluster or collection of related concepts (Bartlett, 1932). There are many different types of schemata, and they all have one thing in common: schemata are a method of organizing information that allows the brain to work more efficiently. When a schema is activated, the brain makes immediate assumptions about the person or object being observed.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigating Dietary Polyphenol Intake in the Australian Population: Results From the 2011-12 National Nutrition and Physical Activity Survey.

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association·2026
Same author

Exposure to Global Burden of Disease dietary factors and risk of recurrent depressive symptoms: the prospective Whitehall II cohort study.

European journal of nutrition·2026
Same author

Adherence to Australian diet, physical activity and alcohol guidelines is associated with lower risk of depression and anxiety: a secondary analysis of the CALM trial.

International journal of food sciences and nutrition·2026
Same author

Dietary interventions and the gut microbiota: a systematic literature review of 80 controlled clinical trials.

Journal of translational medicine·2026
Same author

Polyphenol intake and depressive symptoms in young adults: evidence from a population-based longitudinal study.

The British journal of nutrition·2025
Same author

Effects of a probiotic fermented dairy product on hippocampal metabolites, structure and function: an 8-week randomised, placebo-controlled trial in healthy women.

Gut·2025
Same journal

Wearable device-telemonitored Baduanjin for chronic heart failure: A systematic review of effects on exercise tolerance and cardiac function.

Complementary therapies in medicine·2026
Same journal

Effects of laughter therapy in patients with cancer: A systematic review of randomized clinical trials.

Complementary therapies in medicine·2026
Same journal

Impact of physical exercise interventions on post-traumatic stress disorder symptoms: A systematic review and meta-analysis.

Complementary therapies in medicine·2026
Same journal

Effects of traditional Chinese exercises on sleep quality among post-stroke survivors: A systematic review and meta-analysis.

Complementary therapies in medicine·2026
Same journal

Effect of head and facial massage combined with aromatherapy on sleep quality and delirium in patients with acute myocardial infarction: A randomized controlled trial.

Complementary therapies in medicine·2026
Same journal

Cognitive improvement by daily intake of coffee cherry pulp extract from Coffea canephora var. Robusta in a Japanese population: A randomized, placebo-controlled, double-blind, parallel-group comparison trial.

Complementary therapies in medicine·2026
See all related articles

Related Experiment Videos

Dietary selenium and major depression: a nested case-control study.

Julie A Pasco1, Felice N Jacka, Lana J Williams

  • 1School of Medicine, Deakin University, Geelong, Victoria 3220, Australia. juliep@barwonhealth.org.au

Complementary Therapies in Medicine
|April 17, 2012
PubMed
Summary
This summary is machine-generated.

Low dietary selenium intake is linked to a higher risk of developing major depressive disorder (MDD). This suggests selenium may be a modifiable factor in depression prevention and management.

Related Experiment Videos

Area of Science:

  • Nutritional Science
  • Psychiatry
  • Epidemiology

Background:

  • Redox biology plays a role in depression.
  • Prospective epidemiological data on selenium and depression are lacking.
  • Selenium is a redox-active trace element crucial for antioxidant functions.

Purpose of the Study:

  • To investigate the association between dietary selenium intake and the risk of developing new-onset major depressive disorder (MDD).
  • To determine if low selenium levels are a risk factor for de novo MDD in women.

Main Methods:

  • Nested case-control study within a prospective cohort of women aged 20+.
  • Incident MDD identified using the Structured Clinical Interview for DSM-IV-TR (SCID-I/NP).
  • Dietary selenium intake assessed via food frequency questionnaire; anthropometric and lifestyle data collected.

Main Results:

  • Eighteen incident MDD cases and 298 controls were analyzed.
  • Low dietary selenium intake was associated with an increased likelihood of developing MDD (OR 2.74).
  • After adjustments, low selenium intake (<8.9 μg/MJ/day) nearly tripled the risk of de novo MDD (OR 2.95), independent of smoking, alcohol, or physical activity.

Conclusions:

  • Lower dietary selenium intake is associated with an increased risk of subsequent de novo MDD.
  • Selenium's antioxidant and selenoprotein functions suggest its potential role in redox homeostasis and depression.
  • Dietary selenium may represent a novel, modifiable factor for depression's primary prevention and management.