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Updated: May 23, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Perioperative management of the pediatric patient with traumatic brain injury
Tarun Bhalla1, Elisabeth Dewhirst, Amod Sawardekar
1Departments of Anesthesiology, Nationwide Children's Hospital and the Ohio State University, Columbus, OH, USA tarun.bhalla@nationwidechildrens.org
Insights
Pediatric traumatic brain injury (TBI) management requires careful perioperative care. This review details evidence-based guidelines for stabilizing and treating children with TBI to improve outcomes.
Area of Science:
- Pediatric Anesthesiology
- Neurocritical Care
- Trauma Surgery
Background:
- Traumatic brain injury (TBI) presents a significant global health challenge.
- Advances in understanding TBI pathophysiology and monitoring have improved patient prognoses.
- Existing guidelines for acute TBI management exist, but perioperative considerations require specific attention.
Purpose of the Study:
- To review evidence-based medicine for the perioperative care of pediatric patients with TBI.
- To provide management recommendations for pediatric TBI in the perioperative setting.
- To ensure pediatric anesthesiologists are familiar with guidelines to prevent secondary TBI damage.
Main Methods:
- Comprehensive literature review of current evidence-based medicine.
- Focus on pediatric TBI management relevant to perioperative care.
- Synthesis of information on stabilization, airway, ventilation, hemodynamics, and anesthetic techniques.
Main Results:
- The review covers critical aspects including initial stabilization, airway management, intraoperative ventilation, hemodynamic support, blood product administration, patient positioning, and anesthetic choices.
- Evidence regarding fluid management, glucose control, hyperosmolar therapy, therapeutic hypothermia, and corticosteroid use is examined.
- Management recommendations are provided where supported by current literature.
Conclusions:
- Familiarity with TBI management guidelines is crucial for pediatric anesthesiologists.
- Optimizing perioperative care can mitigate preventable secondary brain injury in pediatric TBI patients.
- This review offers a practical guide for evidence-based perioperative management of pediatric TBI.
Abstract:
TBI and its sequelae remain a major healthcare issue throughout the world. With an improved understanding of the pathophysiology of TBI, refinements of monitoring technology, and ongoing research to determine optimal care, the prognosis of TBI continues to improve. In 2003, the Society of Critical Care Medicine published guidelines for the acute management of severe TBI in infants, children, and adolescents. As pediatric anesthesiologists are frequently involved in the perioperative management of such patients including their stabilization in the emergency department, familiarity with these guidelines is necessary to limit preventable secondary damage related to physiologic disturbances. This manuscript reviews the current evidence-based medicine regarding the care of pediatric patients with TBI as it relates to the perioperative care of such patients. The issues reviewed include those related to initial stabilization, airway management, intra-operative mechanical ventilation, hemodynamic support, administration of blood and blood products, positioning, and choice of anesthetic technique. The literature is reviewed regarding fluid management, glucose control, hyperosmolar therapy, therapeutic hypothermia, and corticosteroids. Whenever possible, management recommendations are provided.
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