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Updated: May 23, 2026

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation
Published on: September 4, 2017
BioDoser: improved dose-estimation software for biological radiation dosimetry
Hong Wang1, Qiang Liu, Dandan Wan
1Department of Radiation Hazard Evaluation, Institute of Radiation Medicine of Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192, China.
Abstract:
This paper introduces a software program that was developed with the aims to improve the efficiency and veracity of calibration curve fitting and data processing in radiation biological dosimetry and other biological experiments, and which is termed BioDoser. BioDoser uses least squares and loop testing of monotonicity method and algorithm of non-uniformed confidence interval. In addition, this program enables integration of multiple different biomarkers typically used in biological dosimetry. These include partial body exposure, minimum number of cells to be analyzed, G function correction modules that are helpful in dose estimation when using chromosome aberration frequencies, micronucleus rate, comet assay and other biological methods. The software is freely available at http://bit.ly/kKBSNR.
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