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Updated: May 23, 2026

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
Published on: November 30, 2015
Analysis of blood-based gene expression signature in first-episode psychosis
Jimmy Lee1, Liang-Kee Goh, Gengbo Chen
1Department of General Psychiatry 1 & Research Division, Institute of Mental Health/Woodbridge Hospital, and Office of Clinical Sciences, Duke-National University of Singapore Graduate Medical School, Singapore. jimmy_lee@imh.com.sg
Abstract:
Blood-based transcriptomic signature in psychosis is an alternative to a brain-based signature. In this study, we profiled whole-blood RNA from 26 patients with first-episode psychosis, and 26 matching controls. We identified a 400-gene signature that classified patients from controls accurately and tested the robustness using other modelling methods.
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