[Arterial blood flow changes after hyperthermia on normal liver, normal brain, and normal small intestine]

Arterial blood flow changes are studied after hyperthermia on normal liver, normal brain, and normal small intestine. A small part in left lateral lobe of rat liver was heated by RF capacity heating. Arterial blood flow in heated area of liver decreased to 69.2 +/- 8.1 and 51.3 +/- 6.6 ml/min/100 g dry weight respectively after heating at 43 degrees C for 30 min and 45 min, from 83.1 +/- 2.6 ml/min/100 g dry weight at 37 degrees C. To heat a small part in left hemisphere of rat cerebral tissue, RF interstitial heating device was utilized. Arterial blood flow in heated area increased to 289.1 +/- 41.5 ml/min/100 g dry weight after heating at 42 degrees C for 30 min from 223.6 +/- 18.8 ml/min/100 g dry weight at 37 degrees C. For small intestine heating, water bath was used. Arterial blood flow increased to 6.60 +/- 1.36, 7.44 +/- 1.16, and 11.6 +/- 2.2 ml/min/g dry weight respectively after heating at 39 degrees C, 41 degrees C, and 43 degrees C for 30 min, from 5.04 +/- 0.85 ml/min/g dry weight at 37 degrees C. These data suggest that blood flow changes after hyperthermia differ from tissue to tissue, and require further investigation on the effect of hyperthermia on blood flow changes in liver, brain, small intestine, and other normal tissues.