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Updated: May 23, 2026

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Synthesis, spectral characterization and antimicrobial evaluation of Schiff base Cr (III), Mn (III) and Fe (III)
Gajendra Kumar1, Shoma Devi, Rajeev Johari
1Department of Chemistry, Vardhaman College, Bijnor 246701, Uttar Pradesh, India. gaj.chem@gmail.com
Abstract:
A Schiff base ligand was synthesized by reacting 1,4-dicarbonyl-phenyl-dihydrazide and chromene-2,3-dione (2:2) and a series of metal complexes with this new ligand were synthesized by reaction with Cr (III), Mn (III), and Fe (III) metal salt in methanolic medium. The Schiff base ligand and its metal complexes have been characterized with the help of elemental analysis, conductance measurements, magnetic measurements and their structure configuration has been determined by various spectroscopic (electronic, IR, (1)H NMR, (13)C NMR, GCMS) techniques. Electronic spectra of the complexes indicate that the geometry of the metal center was five coordinate square pyramidal. These metal complexes were also tested for their antimicrobial activities to assess their inhibiting potential.
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