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Updated: May 23, 2026

Real-time Analyses of Retinol Transport by the Membrane Receptor of Plasma Retinol Binding Protein
Published on: January 28, 2013
Where is the vitamin D receptor?
Yongji Wang1, Jinge Zhu, Hector F DeLuca
1Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706, USA. yongjiwang@wisc.edu
The vitamin D receptor (VDR) is crucial for vitamin D
Area of Science:
- Endocrinology and Molecular Biology
Background:
- The vitamin D receptor (VDR) is a nuclear receptor superfamily member.
- VDR mediates the biological actions of vitamin D, regulating genes for calcium homeostasis, cell growth, and immunity.
Purpose of the Study:
- To review the tissue- and cell type-specific distribution of VDR.
- To understand the global function of the vitamin D system in health and disease.
Main Methods:
- Literature review on VDR distribution studies.
- Analysis of VDR expression patterns across various tissues and cell types.
Main Results:
- VDR is detected in numerous tissues and cell types.
- VDR distribution is specific to tissue and cell type, indicating targeted roles.
Conclusions:
- VDR distribution is widespread but cell-type specific.
- Understanding VDR localization is key to elucidating vitamin D's role in physiology and pathology.
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