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Updated: May 23, 2026

Ultrasound Imaging of the Thoracic and Abdominal Aorta in Mice to Determine Aneurysm Dimensions
Published on: March 8, 2019
Thoracic and abdominal aortic diameter measurement by MRI using plain axial volumetric interpolated breath-hold
Birger Mensel1, Katrin Hegenscheid, Lydia Hesselbarth
1Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Germany. birger.mensel@uni-greifswald.de
Rationale And Objectives:
This study evaluates the validity and reliability of measuring the diameters of the thoracic and abdominal aorta from plain volumetric interpolated breath-hold examination (VIBE) images.
Materials And Methods:
The study included 50 male subjects from the population-based Study of Health in Pomerania. They underwent imaging of the thoracic and abdominal aorta at 1.5 Tesla using a contrast-enhanced magnetic resonance angiography (CE-MRA) and plain VIBE sequence. Diameters were measured at five predefined anatomic sites from reformatted orthogonal CE-MRA images and axial plain VIBE images. The measurements were validated using Pearson correlation and Bland-Altman analysis. The Bland-Altman method was also used to assess reliability.
Results:
Comparison of the diameters measured from CE-MRA and VIBE images revealed strong correlation for the ascending, descending, suprarenal, and infrarenal aorta with r = 0.95 (P < .0001), r = 0.88 (P < .0001), 0.92 (P < .0001), and 0.87 (P < .0001), respectively. Measurement for the aortic arch was moderately correlated with r = 0.78 (P < .0001). Mean bias did not exceed 0.1 cm (6%). The 95% limits of agreement (LOA) were less than 0.5 cm (15%). Intra- and interobserver agreement showed a mean bias of less than 2%; the 95% LOA were less than 11%.
Conclusions:
Axial measurement of the diameters of the thoracic and abdominal aorta using a plain axial VIBE sequence is highly valid and reliable, making it suitable for use in epidemiologic research.
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