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Related Concept Videos

Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...
Lipid-derived Compounds in the Human Body01:31

Lipid-derived Compounds in the Human Body

Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various  biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin, delayed...
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
What are Lipids?01:38

What are Lipids?

Overview

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Updated: May 23, 2026

Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells
09:34

Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells

Published on: February 9, 2019

Lipids and prostate cancer.

Janel Suburu1, Yong Q Chen

  • 1Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

Prostaglandins & Other Lipid Mediators
|April 17, 2012
PubMed
Summary
This summary is machine-generated.

Prostate cancer exhibits increased de novo lipid synthesis, a key metabolic shift supporting cancer growth. Further research is needed to understand how dietary fats interact with these cancer-produced lipids.

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miRNA Expression Analyses in Prostate Cancer Clinical Tissues
11:29

miRNA Expression Analyses in Prostate Cancer Clinical Tissues

Published on: September 8, 2015

Area of Science:

  • Oncology
  • Metabolic Research
  • Biochemistry

Background:

  • Prostate cancer is characterized by a unique upregulation of de novo lipid synthesis.
  • Cancer cells exhibit a metabolic shift, utilizing alternative pathways for fatty acid production.
  • Newly synthesized lipids are crucial for prostate cancer cell proliferation and survival, making de novo lipogenesis a therapeutic target.

Purpose of the Study:

  • To highlight the lipogenic nature of prostate cancer.
  • To emphasize the promotion of de novo lipid synthesis in prostate cancer.
  • To discuss the significance of dietary lipids in prostate cancer development and progression.

Main Methods:

  • Literature review on lipid metabolism in prostate cancer.
  • Analysis of studies on de novo lipogenesis pathways.
  • Examination of epidemiological data on dietary fat intake and prostate cancer.

Main Results:

  • Prostate cancer cells exhibit a pronounced lipogenic phenotype.
  • De novo lipid synthesis is significantly upregulated and supports cancer progression.
  • The differential metabolism of dietary versus endogenously synthesized lipids remains an area requiring further investigation.

Conclusions:

  • De novo lipogenesis is a hallmark of prostate cancer, critical for its growth and survival.
  • Dietary lipids may influence prostate cancer, but their metabolic interplay with cancer-derived lipids is not fully understood.
  • Understanding these lipid metabolic pathways offers potential therapeutic strategies for prostate cancer.