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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

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Detection of Anti-MDA5 Autoantibodies Using HeLa Cells and Immunocytochemistry with Light Microscopy
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Detection of Anti-MDA5 Autoantibodies Using HeLa Cells and Immunocytochemistry with Light Microscopy

Published on: October 31, 2025

Dermatomyositis.

Satveer Mahil1, Daniel Marks, Mary McCormack

  • 1satveer.mahil@gmail.com

British Journal of Hospital Medicine (London, England : 2005)
|April 17, 2012
PubMed
Summary
This summary is machine-generated.

Dermatomyositis is an inflammatory myopathy causing muscle and skin inflammation. Its association with cancer requires careful screening for underlying neoplasia in all patients.

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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

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Detection of Anti-MDA5 Autoantibodies Using HeLa Cells and Immunocytochemistry with Light Microscopy
10:55

Detection of Anti-MDA5 Autoantibodies Using HeLa Cells and Immunocytochemistry with Light Microscopy

Published on: October 31, 2025

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Area of Science:

  • Rheumatology
  • Neurology
  • Dermatology

Background:

  • Dermatomyositis is an idiopathic acute inflammatory disorder.
  • It is characterized by skeletal muscle inflammation, progressive symmetrical proximal myopathy, and cutaneous manifestations.
  • This condition affects both children and adults, with a higher prevalence in women.

Purpose of the Study:

  • To summarize the key characteristics of dermatomyositis.
  • To highlight its prevalence and demographic distribution.
  • To emphasize the critical association with malignancy.

Main Methods:

  • Literature review of dermatomyositis.
  • Analysis of epidemiological data.
  • Review of clinical manifestations and diagnostic considerations.

Main Results:

  • Dermatomyositis is the most common inflammatory myopathy across all age groups.
  • Estimated prevalence is 0.6-1.0 per 100,000 individuals.
  • A significant association with malignancy necessitates thorough oncological screening.

Conclusions:

  • Dermatomyositis requires comprehensive evaluation due to its potential link with cancer.
  • Early detection and management are crucial for affected individuals.
  • Further research into the pathogenesis and treatment is warranted.