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Triazole phosphohistidine analogues compatible with the Fmoc-strategy

Tom E McAllister1, Michael E Webb

  • 1Astbury Centre for Structural Molecular Biology and School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.

Organic & Biomolecular Chemistry
|April 17, 2012
PubMed
Summary

Researchers developed new methods to create antibodies for studying histidine phosphorylation, a crucial process in bacterial signaling. These new chemical approaches are compatible with standard peptide synthesis, enabling broader research into this important post-translational modification.

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