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Related Concept Videos

Exercise and Muscle Performance01:27

Exercise and Muscle Performance

Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...

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Updated: May 23, 2026

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
09:01

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach

Published on: June 5, 2010

Exercise training in juvenile dermatomyositis.

Clarissa Harumi Omori1, Clovis Artur Almeida Silva, Adriana Maluf Elias Sallum

  • 1University of Sao Paulo, Brazil.

Arthritis Care & Research
|April 17, 2012
PubMed
Summary

Supervised exercise significantly improves physical function, bone density, and quality of life in children with juvenile dermatomyositis (DM). This 12-week program enhances aerobic capacity and reduces disease activity in juvenile DM patients.

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In Vivo Canine Muscle Function Assay
09:34

In Vivo Canine Muscle Function Assay

Published on: April 5, 2011

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Last Updated: May 23, 2026

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
09:01

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach

Published on: June 5, 2010

In Vivo Canine Muscle Function Assay
09:34

In Vivo Canine Muscle Function Assay

Published on: April 5, 2011

Area of Science:

  • Pediatric Rheumatology
  • Exercise Physiology
  • Rehabilitation Medicine

Background:

  • Juvenile dermatomyositis (DM) is a chronic autoimmune disease affecting children.
  • Limited research exists on the impact of exercise interventions in this population.
  • Patients often experience muscle weakness, reduced physical capacity, and impaired quality of life.

Purpose of the Study:

  • To evaluate the effects of a supervised exercise program on health parameters in children with mild, chronic juvenile DM.
  • To assess improvements in physical capacity and health-related quality of life.

Main Methods:

  • A prospective longitudinal study involving 10 children with mild, chronic juvenile DM.
  • A 12-week program of twice-weekly aerobic and resistance training.
  • Assessment of muscle strength, function, aerobic conditioning, body composition, disease activity, and quality of life at baseline and post-intervention.

Main Results:

  • Significant improvements in child and parent-reported quality of life scores.
  • Reduced disease activity and improved muscle assessment scores.
  • Enhanced peak oxygen consumption, time-to-exhaustion, and muscle strength.
  • Increased bone mineral apparent density in the whole body and lumbar spine.

Conclusions:

  • A 12-week supervised exercise program is safe for children with mild, chronic juvenile DM.
  • Exercise effectively improves muscle strength and function, aerobic conditioning, and bone mass.
  • The program leads to better disease control and enhanced health-related quality of life.