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A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity

Joshua Wollam1, Daniel B Magner, Lilia Magomedova

  • 1Department of Molecular and Cellular Biology, Huffington Center on Aging, Baylor College of Medicine, Houston, Texas, United States of America.

Plos Biology
|April 17, 2012
PubMed
Summary

Scientists discovered a new enzyme, DHS-16, that regulates longevity in C. elegans by controlling bile acid-like steroid production. This finding offers potential new targets for manipulating lifespan in animals.

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