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Related Concept Videos

Pathophysiology of Vomiting01:22

Pathophysiology of Vomiting

Vomiting is a complex physiological response to expel harmful or irritating substances from the body. It's a defensive mechanism triggered by stimuli like poisons, microbial toxins, cytotoxic drugs, and mechanical abdominal distension. The process is centrally coordinated by the vomiting (or emetic) center located in the medulla of the brainstem. This area, rich in muscarinic M1, histamine H1, neurokinin 1 (NK1), and serotonin 5-HT3 receptors, coordinates the act of vomiting through interaction...
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists01:27

Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists

5-HT3 receptor antagonists, such as dolasetron, granisetron (Kytril), ondansetron (Zofran), and palonosetron (Axoli), are crucial in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea. These drugs selectively block 5-HT3 receptors in the visceral vagal and spinal afferent nerves, chemoreceptor trigger zone, and the vomiting center. They have a rapid onset of action and can be given as a single dose before chemotherapy. Ondansetron and granisetron, in particular,...
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...

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Related Experiment Video

Updated: May 23, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
04:38

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Cyclic vomiting syndrome developed after stroke.

Kwang Lae Lee1, Jung In Shin

  • 1Department of Rehabilitation Medicine, National Rehabilitation Hospital, Seoul 142-884, Korea.

Annals of Rehabilitation Medicine
|April 17, 2012
PubMed
Summary

Cyclic vomiting syndrome (CVS) can occur after stroke. This case study details a 69-year-old woman whose CVS symptoms were successfully managed with imipramine hydrochloride after a left cerebral infarct.

Keywords:
Cyclic vomiting syndromeStroke

Related Experiment Videos

Last Updated: May 23, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
04:38

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Area of Science:

  • Neurology
  • Gastroenterology

Background:

  • Cyclic vomiting syndrome (CVS) is defined by recurrent, stereotyped vomiting episodes with regular symptom-free intervals.
  • The association between stroke and the development of CVS is not well-documented.

Purpose of the Study:

  • To report a novel case of cyclic vomiting syndrome (CVS) developing subsequent to a stroke.
  • To highlight a potential, previously unreported, neurological complication of cerebrovascular events.

Main Methods:

  • A case study approach was used, focusing on a 69-year-old female patient.
  • Diagnosis of CVS was established through exclusion of other potential causes of vomiting post-stroke.
  • Treatment efficacy was assessed based on symptom control.

Main Results:

  • The patient experienced recurrent vomiting following a left cerebral infarct.
  • The vomiting pattern met the diagnostic criteria for cyclic vomiting syndrome (CVS).
  • Imipramine hydrochloride effectively controlled the patient's CVS symptoms.

Conclusions:

  • This case suggests that cyclic vomiting syndrome (CVS) can be a sequela of stroke.
  • Cerebrovascular events, such as cerebral infarcts, may trigger or unmask CVS.
  • Imipramine hydrochloride demonstrates potential efficacy in managing post-stroke CVS.