Euprolactinemic Gynecomastia and Galactorrhea with Risperidone-Fluvoxamine Combination

Area of Science:

• Endocrinology
• Psychiatry
• Pharmacology

Background:

• Risperidone is known to cause hyperprolactinemia and related symptoms like gynecomastia in adults.
• Adverse effects are less common in adolescents, and serotonin reuptake inhibitors rarely cause these symptoms.

Observation:

• A case of gynecomastia and galactorrhea is presented in an adolescent male patient.
• The patient was concurrently treated with both risperidone and fluvoxamine.

Findings:

• The adolescent male experienced gynecomastia and galactorrhea.
• Serum prolactin levels were within the normal range despite the observed symptoms.

Implications:

• This case highlights the potential for risperidone-induced hyperprolactinemia symptoms in adolescents, even with normal prolactin levels.
• Concurrent use of fluvoxamine may warrant further investigation regarding its role in these adverse effects.