Related Experiment Video
Updated: Feb 9, 2026

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy
Published on: May 27, 2018
Isotope effects and heavy-atom tunneling in the Roush allylboration of aldehydes
Mathew J Vetticatt1, Daniel A Singleton
1Department of Chemistry, Texas A&M University, P.O. Box 30012, College Station, Texas 77842, United States.
Abstract:
Intermolecular (13)C kinetic isotope effects (KIEs) for the Roush allylboration of p-anisaldehyde were determined using a novel approach. The experimental (13)C KIEs fit qualitatively with the expected rate-limiting cyclic transition state, but they are far higher than theoretical predictions based on conventional transition state theory. This discrepancy is attributed to a substantial contribution of heavy-atom tunneling to the reaction, and this is supported by multidimensional tunneling calculations that reproduce the observed KIEs.
Related Concept Videos
Isotopes
An element's atomic mass, or weight,...
Atomic Radii and Effective Nuclear Charge
Elements: Chemical Symbols and Isotopes
Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
Atomic Mass
Atomic Spectroscopy: Effects of Temperature
At thermal equilibrium, the relative populations of excited and ground state atoms can be estimated using the Maxwell–Boltzmann distribution. For example, an increase in temperature...
The Energies of Atomic Orbitals

