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Preterm preeclampsia: 32 to 37 weeks gestation.

Angie C Jelin¹, Anjali J Kaimal, Michael Kuzniewicz

¹Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA 94143, USA. jelina@peds.ucsf.edu

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

|April 18, 2012

Summary

Preeclampsia significantly impacts late preterm infant outcomes, increasing risks of being small for gestational age and intensive care admission, but reducing neonatal death rates compared to other preterm delivery causes.

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Published on: November 20, 2015

Area of Science:

Obstetrics and Gynecology
Neonatology
Perinatal Medicine

Background:

Preeclampsia is a serious pregnancy complication.
Late preterm infants (32-36 weeks gestation) face unique neonatal challenges.
Understanding preeclampsia's specific impact on this population is crucial.

Purpose of the Study:

To evaluate neonatal outcomes in late preterm infants delivered due to preeclampsia.
To compare these outcomes with infants delivered prematurely for other reasons.

Main Methods:

Retrospective cohort study of 3580 infants (32 0/7 to 36 6/7 weeks gestation).
Comparison of neonatal outcomes between infants delivered due to preeclampsia and other etiologies.
Multivariate logistic regression analysis to determine associations.

Main Results:

Infants born to mothers with preeclampsia had higher rates of Small for Gestational Age (SGA) (26.8% vs. 8.4%).
Higher admission rates to the Intensive Care Nursery (ICN) were observed in the preeclampsia group (54.3% vs. 39.0%).
Neonatal death rates were lower in infants of preeclamptic mothers (2.2% vs. 3.4%), while Respiratory Distress Syndrome (RDS) rates were similar.

Conclusions:

Neonatal outcomes for late preterm infants born due to preeclampsia differ significantly from those born for other indications.
Preeclampsia presents a distinct risk profile for late preterm neonates, including increased SGA and ICN admissions but decreased mortality.