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Published on: November 16, 2016

An Arthrobacter spp. bacteremia leading to fetal death and maternal disseminated intravascular coagulation

Naoya Shigeta1, Kimiaki Ozaki, Kensuke Hori

  • 1Department of Obstetrics and Gynecology, Kansai Rosai Hospital, Amagasaki, Japan.n shigeta@kanrou.net

Fetal and Pediatric Pathology
|April 18, 2012
PubMed

A 34-year-old parous woman developed high fever and threatened preterm labor after a 1-day trip, for which she was receiving prenatal care at a hospital. Three days after onset, at 24 4/7 weeks of gestation, she was transferred to our hospital in an emergency. Soon after the woman's arrival at our hospital, the infant was spontaneously stillborn via a transvaginal delivery. Laboratory tests revealed severe maternal disseminated intravascular coagulation with renal and liver insufficiency. Histopathologic examination of the placenta revealed vast fibrin deposition and remarkable neutrophilic infiltration in the intervillous space, suggesting a rare bacterial infection caused by Arthrobacter spp. The bacteria were predominantly detected in the placenta and maternal blood serum by common bacterial 16S rRNA sequencing after polymerase chain reaction amplification. We report the first case, to our knowledge, of bacteremia with Arthrobacter spp., which may lead to maternal disseminated intravascular coagulation and intrauterine fetal death.

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