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Non-Hodgkin's lymphoma and 1,25(OH)2D-related hypercalcaemia
M E Craanen1, L van Beugen, P Blok
1Department of Internal Medicine, St Elisabeth of Groote Gasthuis, Haarlem.
The Netherlands Journal of Medicine
|October 1, 1990
Summary
This study describes a patient with non-Hodgkin's lymphoma who experienced hypercalcemia and elevated 1,25(OH)2D levels. Both conditions resolved after treatment, suggesting a link between calcitriol and immune regulation in lymphoma.
Area of Science:
- Endocrinology
- Oncology
- Immunology
Background:
- Hypercalcemia is a known complication in some hematologic malignancies.
- The role of vitamin D metabolites in cancer and immune function is an area of active research.