Related Experiment Video
Updated: May 23, 2026

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens
Published on: May 19, 2020
[History of compulsory immunization]
Silvio Tafuri1, Domenico Martinelli, Cinzia Germinario
1Dipartimento di Scienze Biomediche e Oncologia Umana, Università degli Studi di Bari Aldo Moro.
Abstract:
Mandatory vaccination was introduced for the first time in the nineteenth century in some European countries following the then sweeping smallpox epidemics. Compulsory vaccination for some diseases is still extant in some countries like Italy, France, Greece, Portugal and Belgium; in other countries, like the United Kingdom and Finland, vaccinations are voluntary but the state pursues a policy of active promotion. In 2007, the Veneto Region of Italy government approved a law allowing the experimentation of the abolition of mandatory vaccination. This experimentation caused an important debate among healthcare workers and scientific society of public health.
Related Concept Videos
Vaccinations
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
History of Microbiology
Vaccines
Immunological Memory
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...

