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Bacterial Signaling01:30

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...

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Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
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Published on: October 20, 2021

Towards biodegradable wireless implants.

Clémentine M Boutry1, Hengky Chandrahalim, Patrick Streit

  • 1Micro and Nanosystems, Department of Mechanical and Process Engineering, ETH Zurich, Switzerland. clementine.boutry@micro.mavt.ethz.ch

Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
|April 18, 2012
PubMed
Summary
This summary is machine-generated.

New biodegradable implants offer temporary solutions, avoiding removal surgeries for enhanced patient comfort and safety. This research explores challenges and designs for fully biodegradable wireless sensors.

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Area of Science:

  • Biomaterials Science
  • Medical Device Engineering
  • Implant Technology

Background:

  • Temporary medical implants aim to eliminate secondary removal surgeries.
  • Biodegradable devices enhance patient safety and comfort by dissolving naturally.
  • Advancements are needed to overcome technological challenges in creating biodegradable components.

Purpose of the Study:

  • To provide a state-of-the-art overview of biodegradable implant technology.
  • To identify and address key technological challenges in developing biodegradable devices.
  • To explore concepts for partially and fully biodegradable wireless implants, focusing on in vivo sensing.

Main Methods:

  • Review of current literature on biodegradable materials and device design.
  • Experimental synthesis and characterization of biodegradable resistor-inductor-capacitor (RLC) resonators.
  • Utilizing biodegradable metals (Mg, Fe alloys) and conductive polymer composites (PCL-PPy, PLA-PPy).

Main Results:

  • Demonstrated feasibility of fabricating biodegradable RLC resonators using selected metals and polymer composites.
  • Identified critical design and synthesis considerations for biodegradable electronic components.
  • Explored two conceptual frameworks for biodegradable wireless implantable devices.

Conclusions:

  • Biodegradable implants represent a significant advancement in patient care, reducing surgical burden.
  • Development of biodegradable conductive materials and device architectures is crucial for future applications.
  • The ultimate goal is the realization of fully biodegradable wireless sensors for in vivo monitoring.