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Updated: May 23, 2026
Studying Murine Small Bowel Mechanosensing of Luminal Particulates
Published on: March 18, 2022
Diagnostic yield of small bowel capsule endoscopy depends on the small bowel transit time
Jessie Westerhof1, Jan J Koornstra, Reinier A Hoedemaker
1Department of Gastroenterology and Hepatology, University Medical Center, University of Groningen, Groningen, The Netherlands.
Aim:
To investigate whether the small bowel transit time (SBTT) influences the diagnostic yield of capsule endoscopy (CE).
Methods:
Six hundred and ninety-one consecutive CE procedures collected in a database were analyzed. SBTT and CE findings were recorded. A running mean for the SBTT was calculated and correlated to the diagnostic yield with a Spearman's correlation test. Subgroup analyses were performed for the various indications for the procedure.
Results:
There was a positive correlation between the diagnostic yield and SBTT (Spearman's rho 0.58, P < 0.01). Positive correlations between diagnostic yield and SBTT were found for the indication obscure gastrointestinal bleeding (r = 0.54, P < 0.01), for polyposis and carcinoid combined (r = 0.56, P < 0.01) and for the other indications (r = 0.90, P <0.01), but not for suspected Crohn's disease (r = -0.40).
Conclusion:
The diagnostic yield in small bowel capsule endoscopy is positively correlated with the small bowel transit time. This is true for all indications except for suspected Crohn's disease.
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