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Updated: May 23, 2026

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
Published on: April 9, 2018
Lewis acid-catalyzed, copper(II)-mediated synthesis of heteroaryl thioethers under base-free conditions
Chao Dai1, Zhaoqing Xu, Fei Huang
1Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
Abstract:
A Lewis acid (Ag(I), Ni(II), or Fe(II)) catalyzed, Cu(II)-mediated thiolation reaction between heteroarenes and thiols was achieved with good yield under base-free conditions. DMSO could serve as an effective methylthiolation reagent for the synthesis of heterocyclic methyl thioethers.
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