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Osteopenia and phenylketonuria
D J Carson1, L G Greeves, L E Sweeney
1Department of Child Health, Queens University, Belfast, Northern Ireland.
Pediatric Radiology
|January 1, 1990
Abstract:
Trabecular bone mineral content was assessed by quantitative computed tomography in eleven young adults with phenylketonuria who had been treated from early childhood with a diet restricted in natural protein and supplemented with amino acids, minerals and vitamins. There was a significant reduction in the bone mineral content of patients compared with the normal population. Prospective studies are indicated in younger patients to ensure optimum bone mineralisation is achieved by adulthood.