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An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
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Related Experiment Video

Updated: May 23, 2026

Visualization and Analysis of Pharyngeal Arch Arteries using Whole-mount Immunohistochemistry and 3D Reconstruction
10:02

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Published on: March 31, 2020

Bilateral first and second arch anomalies: a rare presentation.

Amit Pal Singh1, Virad Kumar, Vineet Narula

  • 1Department of Otorhinolaryngology and Head and Neck Surgery, Maulana Azad Medical College and associated Lok Nayak, GNEC and GB Pant Hospitals, New Delhi 110002, India. dr_amit01@rediffmail.com

Singapore Medical Journal
|April 19, 2012
PubMed
Summary

Bilateral branchial sinuses are rare congenital anomalies. This case highlights the extremely rare co-occurrence of bilateral first and second branchial arch anomalies without a family history or syndrome.

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Area of Science:

  • Medical Genetics
  • Developmental Biology
  • Otolaryngology

Background:

  • Branchial sinuses are common congenital anomalies, typically unilateral.
  • Bilateral branchial sinuses are rare, and their association with other anomalies is even rarer.

Observation:

  • A patient presented with bilateral first branchial arch anomalies.
  • The patient also exhibited bilateral second branchial arch anomalies.

Findings:

  • This case details the extremely rare co-existence of bilateral first and second branchial arch anomalies.
  • The patient had no familial history or identifiable associated syndrome.

Implications:

  • This case expands the understanding of rare congenital anomalies of the branchial arches.
  • Highlights the importance of thorough examination for associated anomalies in branchial sinus cases.
  • Contributes to the literature on rare developmental abnormalities.