Related Experiment Video
Updated: May 23, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Antegrade percutaneous valve implantation for mitral ring dysfunction, a challenging case.
Anna Petronio1, Cristina Giannini, Marco De Carlo
1University of Pisa, Cardiothoracic and Vascular, Pisa, Italy. as.petronio@gmail.com
Reoperative surgery for degenerated bioprosthetic valves carries high risks, especially with comorbidities. Transcatheter mitral valve implantation offers a new option for high-risk patients.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Biomedical Engineering
Background:
- Reoperation for degenerated bioprosthetic valves or mitral-valve annuloplasty failure presents significantly higher operative risks compared to initial valve procedures.
- Comorbidities further amplify these risks, posing substantial challenges in managing patients requiring repeat interventions.
- Transcatheter valve implantation technologies have emerged as a promising alternative for patients deemed inoperable or at extreme risk for conventional surgery.
Observation:
- This case report details a percutaneous mitral valve implantation procedure.
- The implantation utilized a transatrial approach, specifically targeting a degenerated mitral valve annuloplasty ring.
- The Edwards Sapien XT valve was employed for the transcatheter mitral valve implantation.
Findings:
- Percutaneous mitral valve implantation via a transatrial approach within a mitral valve ring is feasible.
- This technique demonstrates a potential solution for high-risk patients with degenerated bioprosthetic valves or failed annuloplasty.
Implications:
- Transcatheter mitral valve interventions may expand treatment options for complex mitral valve disease in high-risk surgical populations.
- Further research and clinical evaluation are warranted to establish the long-term efficacy and safety of this approach.
- This technique could potentially reduce morbidity and mortality associated with reoperative mitral valve surgery.
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