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Updated: May 23, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
Screening and identification of various components in Thalictrum fortunei using a combination of liquid
1Department of Traditional Chinese Medicine, Zhejiang Institute for Food and Drug Control, Hangzhou, P. R. of China.
Abstract:
An approach for screening and identification of various components in a traditional Chinese medicine (TCM), using a combination of LC/TOF-MS technique was described in this paper. The chemical profile of Thalictrum fortunei, well-known in TCM, was studied using the established method. The possibilities of screening and identifying non-target components inside TCM with modern data acquisition methods of acceleration time of flight mass spectrometers, such as data-dependent MS to MS/MS switching were investigated. As a result, 27 components were identified. This study was aimed to screen and identify the main components of T. fortunei using LC/TOF-MS, expecting to provide a rapid, sensitive, economical and systematical method for the identification and further quality evaluation of TCM preparation.
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